Matrix metering and EL

I've read in the manual that using the exposure lock (EL) button in conjunction with matrix metering can give unpredicable results. Can someone explain why this is so?
I usually use the EL button in lock-and-hold mode when shooting multi images for panoramas to hold the exposure for the series of images, and since reading this had reverted to center-weighted metering. If you meter the correct exposure for on image, how can locking the values give unpredicatable results?
Alistair
I usually use the EL button in lock-and-hold mode when shooting multi images for panoramas to hold the exposure for the series of images, and since reading this had reverted to center-weighted metering. If you meter the correct exposure for on image, how can locking the values give unpredicatable results?
Alistair